Next-Generation Separation Technology
Making the Invisible Visible
We support R&D across diverse industries through innovative separation technologies that reveal the unseen.
Our technological innovation is driven by two core pillars:
We offer AqasPrime™, our proprietary capillary monolith column, along with a high-precision, micro-scale analysis system designed for ultra-sensitive separations.
With this platform, researchers can now detect and isolate trace compounds and complex mixtures that were previously undetectable. AqasPrime™ is opening new frontiers in drug discovery, functional food development, and cosmetic ingredient analysis.
Unleashing the Power of Precision Separation
・Features a unique biphasic mechanism combining hydrophobic and hydrophilic interactions
・Delivers sharp, high-resolution chromatographic peaks—even for trace-level, complex mixtures
・Available in a range of configurations tailored to diverse analytical targets
・Enables simultaneous, high-precision separation of hundreds of natural compounds, including plant metabolites
AqasPrime™ is a breakthrough capillary monolithic column (100μm ID) that revolutionizes the analysis of complex natural products previously considered too difficult to separate.
Optimized Performance, Seamlessly Integrated
・Equipped with a proprietary microflow pump engineered to maximize the column’s performance
・Ensures stable low-flow delivery for highly reproducible non-targeted analysis
・Offered as a complete, ready-to-use package combining column and system for streamlined operation
From Unseen Compounds to Shared Knowledge
We are building a proprietary data platform based on the high-precision separation and analysis made possible by AqasPrime™.
Our goal is to create a comprehensive, visualized database of natural compound profiles to support discovery and innovation across research and industry.
The platform is currently under development, and we welcome interest and collaboration from researchers and organizations looking to explore its potential.
If you’re interested in partnering with us or learning more, please don’t hesitate to get in touch.
■ Pioneering High-Precision Data Platforms
Turning Untargeted Analysis into Actionable Knowledge
At our company, we are developing a comprehensive database to systematically store and organize mass spectrometry data derived from AqasPrime™’s high-resolution separations.
Capable of analyzing up to 200 compounds per run and 10 samples per day, our system generates vast, high-density untargeted datasets.
Our aim is to transform this data into a powerful knowledge platform—advancing the discovery of unknown compounds and accelerating research efficiency across fields.
■ Accelerating Drug Discovery at the Molecular Frontier
Unlocking Hidden Potential Through High-Precision Compound Separation
The earliest—and most critical—stage of drug development is seed discovery: identifying promising compounds that could one day become new medicines. However, many of these candidates fail in later stages due to a lack of early, high-quality data. Improving the precision and efficiency of early-stage screening is essential.
Our AqasPrime™ monolithic capillary column enables simultaneous, high-resolution separation of over 200 trace compounds, even from complex natural mixtures.
It visualizes hidden micro-components that are often missed, opening new possibilities for innovative drug seeds.
When paired with LC-MS, AqasPrime gives researchers access to previously unreachable compound groups—bringing unmatched depth to untargeted analysis.
■Pioneering Sustainable Innovation—Dramatically Reducing Solvent Waste in Research
In conventional liquid chromatography, massive volumes of organic solvents are consumed and discarded with every measurement—posing serious challenges for both environmental sustainability and operational costs.
Traditional HPLC systems can generate up to 600 liters of solvent waste per year—roughly the volume of three oil drums—from continuous operation.
With AqasPrime, that waste can be reduced to the equivalent of just one can of beer (approx. 350 mL)—without compromising analytical precision.
This revolutionary low-solvent technology enables:
・ Significant cost savings in research environments
・ Reduction of environmental burden from waste treatment
・ Optimization of research infrastructure for sustainable innovation
AqasPrime™ represents a new era of research tools that align scientific advancement with environmental responsibility.
It directly contributes to UN SDG Goal 9: Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation.
Maximum Scientific Insight from Minimal Samples
The unregulated collection of wild plants in search of drug candidates has become a growing global concern—leading to biodiversity loss and ecological degradation.
In regions like the Himalayas, overharvesting of medicinal plants threatens both environmental sustainability and the future of drug discovery.
Our technology, AqasPrime™, enables high-precision separation and analysis of hundreds of compounds from less than 1 gram of sample.
This next-generation innovation allows researchers to unlock valuable bioactive compounds without overexploiting fragile ecosystems.
By balancing sustainable resource use with cutting-edge scientific exploration, we contribute to UN SDG Goal 3: Ensure healthy lives and promote well-being for all at all ages.